The jaboticaba tree, Plinia trunciflora (O. Berg) Kausel, is popularly named ââ?¬Å?jabuticabeiraââ?¬Â in Brazil and is used in folk medicine to\ntreat diabetes and chronic inflammation of the tonsils, but studies evaluating the central effects of this species are limited. This study\nevaluated the antidepressant-like and antioxidant effects of P. trunciflora (PT) aqueous extract, in which five different anthocyanins\nwere identified. PT showed significant ferric-reduction power and DPPH radical scavenging activity in vitro and reduced lipid\nperoxidation both in vitro and ex vivo. At the behavioural level, PT (400 and 800mg/kg, i.p.) dose-dependently reduced immobility\ntime in the tail suspension test in Swiss male mice. The identification of bioactive compounds accompanied by the in vitro and ex\nvivo antioxidant activity of PT suggests that these activities might be related to the antidepressant-like activity of P. trunciflora.
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